Kalman P G, Taylor B R, Langer B
Can J Surg. 1982 May;25(3):321-4.
Management of iatrogenic stricture of the bile ducts is difficult and is associated with substantial morbidity and mortality. At the Toronto General Hospital, 61 patients with strictures following operative trauma underwent a total of 75 repairs. The overall success rate was 80%. End-to-end duct repair is preferred when feasible; 8 of the 61 patients were treated this way, with success in 7. In the majority of patients, however, extensive duct scarring and shortening preclude its use, necessitating Roux-en-Y hepaticojejunostomy, done in 53 cases. If the anastomosis is adequate, with good mucosal approximation, a stent is not essential and of 12 such operations, 10 were successful. Even when the mucosa-to-mucosa apposition is less than optimal, the use of a straight-tube stent or changeable U-tube stent may produce a satisfactory end result. Of 41 such operations, 31 were successful. Since iatrogenic bile-duct strictures lead to high morbidity and frequent recurrence despite seemingly adequate repair, continued emphasis should be placed on prevention of injury, especially during routine cholecystectomy. Experience, careful dissection, knowledge of anatomic variations and good judgement concerning the performance of a cholecystostomy in difficult situations, should all reduce this complication to a minimum.
医源性胆管狭窄的处理困难,且与较高的发病率和死亡率相关。在多伦多综合医院,61例因手术创伤导致胆管狭窄的患者共接受了75次修复手术。总体成功率为80%。可行时首选端端胆管修复术;61例患者中有8例接受了这种治疗,7例成功。然而,在大多数患者中,广泛的胆管瘢痕形成和缩短使其无法使用,因此有53例患者需要进行Roux-en-Y肝空肠吻合术。如果吻合充分,黏膜贴合良好,则无需放置支架,12例此类手术中有10例成功。即使黏膜对黏膜的贴合不太理想,使用直管支架或可更换的U形管支架也可能产生满意的最终结果。41例此类手术中有31例成功。由于医源性胆管狭窄尽管修复看似充分,但仍会导致高发病率和频繁复发,因此应继续强调预防损伤,尤其是在常规胆囊切除术期间。经验、仔细的解剖、对解剖变异的了解以及在困难情况下对胆囊造口术操作的良好判断,都应将这种并发症降至最低。