异常血红蛋白中的血红素降解
Haem degradation in abnormal haemoglobins.
作者信息
Brown S B, Docherty J C
出版信息
Biochem J. 1978 Sep 1;173(3):985-7. doi: 10.1042/bj1730985.
Abstract
The coupled oxidation of certain abnormal haemoglobins leads to different bile-pigment isomer distributions from that of normal haemoglobin. The isomer pattern may be correlated with the structure of the abnormal haemoglobin in the neighbourhood of the haem pocket. This is support for haem degradation by an intramolecular reaction.
摘要
某些异常血红蛋白的偶联氧化导致胆汁色素异构体分布与正常血红蛋白不同。异构体模式可能与血红素口袋附近异常血红蛋白的结构相关。这支持了通过分子内反应进行血红素降解。
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