Grunwald J E, Sinclair S H, Riva C E
Invest Ophthalmol Vis Sci. 1982 Jul;23(1):124-7.
The autoregulatory response of the retinal circulation to a short-term reduction in intraocular pressure (IOP) to hypotonic levels was studied in 15 normal subjects by means of the blue-field entoptic phenomenon. This phenomenon allows the perception of the leukocytes flowing in one's own retinal macular capillaries. Subjects were asked to compare the leukocyte speed in one eye with that in the fellow eye while a scleral suction cup was used to raise the IOP in one eye to levels above 25 mm Hg for approximately 12 min. The release of the suction cup caused a drop in IOP to levels between 4 and 7 mm Hg, at which time all subjects reported a higher leukocyte speed (hyperemia) in this eye than in the fellow eye. After an average of 4 min the speed was observed to be equal in both eyes. The average IOP at which the equalization occurred was 6.8 +/- 1.3 mm Hg. The retina can therefore normalize leukocyte capillary speed and presumably blood flow at IOPs at least as low as 6.8 mm Hg. The results of 16 experiments on the same eye of one subject suggest that under these experimental conditions, the lowest IOP for which the retina can fully autoregulate is around 6 to 7 mm Hg.
通过蓝场视内现象，在15名正常受试者中研究了视网膜循环对眼压（IOP）短期降至低渗水平的自动调节反应。这种现象使人们能够感知自身视网膜黄斑毛细血管中流动的白细胞。当使用巩膜吸盘将一只眼睛的眼压升高到25毫米汞柱以上约12分钟时，要求受试者比较一只眼睛与另一只眼睛中白细胞的速度。吸盘松开后，眼压降至4至7毫米汞柱之间，此时所有受试者均报告该眼中白细胞速度（充血）高于另一只眼睛。平均4分钟后，观察到两只眼睛的速度相等。速度相等时的平均眼压为6.8±1.3毫米汞柱。因此，视网膜至少在眼压低至6.8毫米汞柱时能够使白细胞毛细血管速度正常化，并可能使血流正常化。对一名受试者同一只眼睛进行的16次实验结果表明，在这些实验条件下，视网膜能够完全自动调节的最低眼压约为6至7毫米汞柱。
