帕金森病患者脑脊液和血浆中γ-氨基丁酸水平
CSF and plasma GABA levels in Parkinson's disease.
作者信息
Abbott R J, Pye I F, Nahorski S R
出版信息
J Neurol Neurosurg Psychiatry. 1982 Mar;45(3):253-6. doi: 10.1136/jnnp.45.3.253.
Abstract
CSF gamma-aminobutyric acid (GABA) levels were reduced in patients with idiopathic Parkinson's disease when compared with age matched controls, but the difference was not significant. However, when the Parkinsonian patients were subdivided, CSF GABA levels were lower in the levodopa treated group than in the untreated group and the controls. There was no difference in plasma GABA levels between Parkinsonian patients and controls.
摘要
与年龄匹配的对照组相比，特发性帕金森病患者脑脊液中γ-氨基丁酸（GABA）水平降低，但差异不显著。然而，当对帕金森病患者进行细分时，左旋多巴治疗组的脑脊液GABA水平低于未治疗组和对照组。帕金森病患者与对照组之间的血浆GABA水平没有差异。
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