Bruynzeel D P, van Ketel W G, Scheper R J, von Blomberg-van der Flier B M
Contact Dermatitis. 1982 Jul;8(4):236-9. doi: 10.1111/j.1600-0536.1982.tb04205.x.
Irritant reactions to sodium lauryl sulfate were induced on the backs of 20 volunteers by means of patch test occlusion for 24 h. Different concentrations ranging from 0.25% to 2% were used, the lowest concentration being borderline irritant. The skin tests were read at 24, 48 and 72 h. Both the % of responding individuals and the intensity of the skin reactions were maximal at 48 h for all test concentrations. It is concluded that irritants may provoke inflammatory reactions which are not completely developed after 24 h, and are thus very similar to allergic patch test reactions.
通过斑贴试验封闭24小时，在20名志愿者的背部诱发对月桂醇硫酸酯钠的刺激反应。使用了0.25%至2%的不同浓度，最低浓度为临界刺激浓度。在24、48和72小时读取皮肤试验结果。对于所有测试浓度，有反应个体的百分比和皮肤反应强度在48小时时均达到最大值。得出的结论是，刺激物可能引发炎症反应，这些反应在24小时后并未完全显现，因此与过敏性斑贴试验反应非常相似。
