Ahrné L, Björck L, Claesson O
Ann Nutr Metab. 1982;26(3):162-70. doi: 10.1159/000176559.
3H-[9,10]-1-O-alkyl-2,3-diacyl glycerols were administered per os to suckling rats at 1, 3, 6, 9 and 18 days of age. 12 h after administration the animals were killed and the distribution of the labelled material was analysed by whole-body autoradiography. The brown adipose tissue (BAT), intestine and liver showed the highest levels of label at all ages. The lipid content of BAT, intestine and liver were separated into lipid classes, which were analysed for their 3H levels. About 30% of the recovered label was found in the phospholipid fraction at all ages. Little of the administered dose was recovered as alkyl glycerols: 5% in the 1-day-old rat decreasing to less than 1.5% at 18 days of age, indicating that dietary alkyl glycerols only to a very limited degree are incorporated in tissue ether lipids in the young rat.
将3H-[9,10]-1-O-烷基-2,3-二酰基甘油经口给予1、3、6、9和18日龄的乳鼠。给药12小时后处死动物，通过全身放射自显影分析标记物的分布。在所有年龄段，棕色脂肪组织（BAT）、肠道和肝脏显示出最高水平的标记。将BAT、肠道和肝脏的脂质含量分离成脂质类别，并分析其3H水平。在所有年龄段，约30%回收的标记物存在于磷脂部分。给药剂量中只有很少一部分以烷基甘油形式回收：1日龄大鼠中为5%，18日龄时降至不到1.5%，这表明膳食中的烷基甘油在幼鼠组织醚脂中的掺入程度非常有限。
