大鼠可移植的分泌IgD免疫球蛋白的肿瘤
Transplantable IgD immunoglobulin-secreting tumors in rat.
作者信息
Bazin H, Beckers A, Urbain-Vansanten G, Pauwels R, Bruyns C, Tilkin A F, Platteau B, Urbain J
出版信息
J Immunol. 1978 Nov;121(5):2077-82.
The LOU/C/Wsl rat inbred strain presents a high incidence of spontaneous malignant ileocecal immunocytomas or monoclonal immunoglobulin-secreting tumors. Some tumors have been transplanted in histocompatible animals over years without any change in their secretion products. Among approximately 600 different monoclonal proteins we have studied so far, we recognized six showing properties different from those of rat IgM, IgA, IgE, or IgG classes, and characteristic of the IgD class.
LOU/C/Wsl近交系大鼠自发性恶性回盲部免疫细胞瘤或单克隆免疫球蛋白分泌肿瘤的发生率很高。多年来，一些肿瘤已被移植到组织相容性动物体内，其分泌产物没有任何变化。在我们目前研究的大约600种不同的单克隆蛋白中，我们识别出六种表现出与大鼠IgM、IgA、IgE或IgG类不同的特性，具有IgD类的特征。
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