Alfredsson L, Ahlbom A, Theorell T
Int J Epidemiol. 1982 Sep;11(3):225-8. doi: 10.1093/ije/11.3.225.
In Finland, the incidence of coronary heart disease is reported to be about twice as high as in the neighbouring country of Sweden. The aim of this study was to find out what happens to this excess risk among Finnish immigrants to Sweden. A geographically defined population in Stockholm County was followed up in the in-patient care registry and the cause-of-death registry in order to find cases for a case-control study. All episodes of myocardial infarction (ICD numbers 410.00 and 410.99) that had occurred in men born between 1911 and 1935 during the period 1974-76 were recorded. An age-matched control group was randomly selected from the population. By means of the civil registration system it was possible to identify country of birth and length of stay in Sweden. Of the 356 cases, 32 (9%) had been born in Finland compared with 55 (6%) of the 887 controls. The overall relative risk for the Finnish immigrants compared with native Swedes was 1.7. For the group of Finnish immigrants who had been in Sweden for 20 years or more the relative risk was 1.3. It was concluded that since the relative risk decreases during the stay in Sweden the environmental factors dominate the explanation of the difference in the relative risk of developing myocardial infarction between Finland and Sweden.
据报道,芬兰冠心病的发病率约为邻国瑞典的两倍。本研究的目的是了解芬兰移民到瑞典后,这种额外风险会发生什么变化。为了找到病例进行病例对照研究,对斯德哥尔摩县一个地理区域界定的人群在住院护理登记处和死亡原因登记处进行了随访。记录了1974年至1976年期间出生于1911年至1935年的男性发生的所有心肌梗死发作(国际疾病分类编号410.00和410.99)。从该人群中随机选择一个年龄匹配的对照组。通过民事登记系统,可以确定出生国家和在瑞典的停留时间。在356例病例中,32例(9%)出生于芬兰,而在887例对照组中,这一比例为55例(6%)。与瑞典本地人相比,芬兰移民的总体相对风险为1.7。对于在瑞典居住20年或更长时间的芬兰移民群体,相对风险为1.3。研究得出结论,由于在瑞典停留期间相对风险降低,环境因素在解释芬兰和瑞典之间患心肌梗死相对风险差异方面占主导地位。