Korner A F, Ruppel E M, Rho J M
Pediatrics. 1982 Dec;70(6):864-9.
With evidence accumulating that the sleep of infants receiving theophylline is sharply reduced, this study tested whether water bed flotation could increase the sleep and attenuate the restlessness of preterm infants treated with theophylline for apnea. Seventeen preterm infants served as their own control, off and on gently oscillating water beds. The infants' sleep and motility were assessed on days 3 and 4 during the experimental and control conditions. While on the water bed, the infants had significantly more quiet and active sleep, shorter sleep latencies, fewer state changes, less restlessness during sleep, less waking activity, and fewer jittery and unsmooth movements. Reductions in wakefulness and state changes on the water bed were significantly greater, the longer the infants were receiving theophylline, but they were unrelated to theophylline levels which, for the group as a whole, were relatively low. Residual apnea was not reduced on the water bed. Although water bed flotation significantly improved the infants' sleep and motility, stable behaviour differences among the infants were observed across the experimental and control conditions.
随着越来越多的证据表明接受茶碱治疗的婴儿睡眠会大幅减少，本研究测试了水床漂浮是否能增加接受茶碱治疗以缓解呼吸暂停的早产儿的睡眠并减轻其躁动。17名早产儿作为自身对照，分别处于关闭和开启的轻度振荡水床上。在实验和对照条件下的第3天和第4天评估婴儿的睡眠和活动情况。在水床上时，婴儿的安静睡眠和活跃睡眠显著增多，睡眠潜伏期缩短，状态变化减少，睡眠期间躁动减少，清醒活动减少，抖动和不平稳动作减少。婴儿接受茶碱治疗的时间越长，在水床上清醒和状态变化的减少就越显著，但这与茶碱水平无关，就整个组而言，茶碱水平相对较低。水床上残留的呼吸暂停并未减少。虽然水床漂浮显著改善了婴儿的睡眠和活动情况，但在实验和对照条件下观察到婴儿之间存在稳定的行为差异。
