Rubin L G, Dezfulian M, Yolken R H
J Clin Microbiol. 1982 Oct;16(4):770-1. doi: 10.1128/jcm.16.4.770-771.1982.
A serum antibody response has not been previously demonstrated after infection with Clostridium botulinum. We developed an enzyme immunoassay for measuring serum antibody to C. botulinum toxins A, B, and E. This assay system detected a specific immunoglobulin G and immunoglobulin M antibody response to C. botulinum toxin in two patients with infant botulism.
此前尚未证实肉毒梭菌感染后会出现血清抗体反应。我们开发了一种酶免疫测定法,用于检测血清中针对肉毒梭菌A、B和E型毒素的抗体。该检测系统在两名婴儿肉毒中毒患者中检测到了针对肉毒梭菌毒素的特异性免疫球蛋白G和免疫球蛋白M抗体反应。