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[病理性肝酶值——妊娠高血压综合征中即将发生宫内胎儿死亡的合适警示症状]

[Pathological liver enzyme values--a suitable warning symptom of imminent intrauterine fetal death in EPH gestosis].

作者信息

Fischl F, Grünberger W

出版信息

Zentralbl Gynakol. 1982;104(20):1282-7.

PMID:7158148
Abstract

Liver functions (bilirubin, SGOT, SGPT, alkaline phosphatase) and electrolyte changes (sodium+, potassium+, calcium+) were tested in a prospective study in all patients admitted to the First Department of the Hospital of Gynaecology and Obstetrics, University of Vienna, throughout 24 months, for moderate, medium or severe EPH gestosis as well as in pregnant women admitted for intra-uterine foetal death. All 102 cases were subdivided by three groups by severity of gestational toxicosis. A somewhat expected insight was gained from comparison of the three groups, in that aggravated severity of EPH gestosis symptoms was accompanied by higher incidence of pathological liver findings. A comparison between these findings, obtained from existing but impaired pregnancies, and findings obtained from women with intra-uterine foetal death showed that certain limit values were pathological, as were some of the routine findings. --Action should be taken to speed up the course of labour and complete delivery, as soon as thresholds are exceeded in foetuses with mature lungs, in order to prevent intrauterine foetal death.

摘要

在一项前瞻性研究中,对维也纳大学妇产医院第一科室收治的所有患者进行了肝功能(胆红素、谷草转氨酶、谷丙转氨酶、碱性磷酸酶)和电解质变化(钠离子、钾离子、钙离子)检测,研究持续了24个月,这些患者包括患有中度、中度或重度妊娠高血压综合征的孕妇以及因宫内胎儿死亡入院的孕妇。所有102例患者根据妊娠中毒症的严重程度分为三组。通过对三组的比较得出了一个 somewhat expected insight,即妊娠高血压综合征症状的严重程度加重伴随着肝脏病理检查结果的更高发生率。将这些来自现有但受损妊娠的检查结果与来自宫内胎儿死亡女性的检查结果进行比较表明,某些极限值是病理性的,一些常规检查结果也是如此。——一旦成熟肺胎儿的阈值被超过,就应采取行动加快产程并完成分娩,以防止宫内胎儿死亡。

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Zentralbl Gynakol. 1982;104(20):1282-7.
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