van der Walle H B, Bensink T
Contact Dermatitis. 1982 Nov;8(6):376-82. doi: 10.1111/j.1600-0536.1982.tb04262.x.
The cross reaction pattern of acrylic monomers was investigated in 20 groups of animals sensitized to a different acrylic monomer. Animals sensitized to one monoacrylate tend to react to other monoacrylates. Reactions to corresponding monomethacrylates (same alcohol group in the ester) or other monomethacrylates did not occur. Some reactions to di(meth)acrylates were observed. A number of animals sensitized to one monomethacrylate reacted to some other monomethacrylates and to monoacrylates. Reactions to di(meth)acrylates were observed. Animals sensitized to di(meth)acrylates showed hardly any positive cross reaction. A universal screening allergen to detect acrylic monomer sensitizations does not exist. The composition of (industrial) products should be made accessible to the occupational dermatologist in order to prevent the undesirable situation in which a patient suspected of having an acrylic monomer sensitization must be tested with a large series of potent allergens in order to detect the real origin of the sensitization.
在20组对不同丙烯酸单体致敏的动物中研究了丙烯酸单体的交叉反应模式。对一种单丙烯酸酯致敏的动物往往会对其他单丙烯酸酯产生反应。对相应的甲基丙烯酸酯（酯中醇基团相同）或其他甲基丙烯酸酯不会发生反应。观察到一些对二（甲基）丙烯酸酯的反应。许多对一种甲基丙烯酸酯致敏的动物对其他一些甲基丙烯酸酯和单丙烯酸酯产生反应。观察到对二（甲基）丙烯酸酯的反应。对二（甲基）丙烯酸酯致敏的动物几乎没有显示出任何阳性交叉反应。不存在用于检测丙烯酸单体致敏的通用筛查变应原。（工业）产品的成分应提供给职业皮肤科医生，以避免出现这样一种不良情况，即怀疑对丙烯酸单体致敏的患者必须用大量强效变应原进行检测，以便确定致敏的真正来源。
