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糖尿病患儿粒细胞的吞噬和杀菌活性

Phagocytic and bactericidal activity of granulocytes in diabetic children.

作者信息

Dziatkowiak H, Kowalska M, Denys A

出版信息

Diabetes. 1982 Dec;31(12):1041-3. doi: 10.2337/diacare.31.12.1041.

Abstract

Phagocytic and bactericidal activity of granulocytes were estimated in granulocytes of normal and diabetic children. The influence of candidal, tuberculin antigens, and staphylococcal antitoxin on these parameters was also tested. Thirty diabetic and forty healthy children made up the study group. Their ages were 6-18 yr. The disease duration was from 1 to 12 yr. Granulocytes from diabetic children demonstrated a normal ability to absorb staphylococcus. On the other hand, the capacity for intercellular killing of bacteria by granulocytes of diabetic children was decreased.

摘要

在正常儿童和糖尿病儿童的粒细胞中评估粒细胞的吞噬和杀菌活性。还测试了念珠菌、结核菌素抗原和葡萄球菌抗毒素对这些参数的影响。30名糖尿病儿童和40名健康儿童组成了研究组。他们的年龄为6至18岁。病程为1至12年。糖尿病儿童的粒细胞显示出正常的吸收葡萄球菌的能力。另一方面,糖尿病儿童粒细胞的细胞内杀菌能力下降。

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