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人类补体成分C6和C7的特性分析

Characterization of human complement components C6 and C7.

作者信息

Discipio R G, Gagnon J

出版信息

Mol Immunol. 1982 Nov;19(11):1425-31. doi: 10.1016/0161-5890(82)90189-4.

Abstract

Human complement components C6 and C7 have been purified and characterized. Component C6 is a single-chain plasma protein of mol. wt 104,800 containing 3.8% carbohydrate and it has alanine as the amino terminal residue. Component C7 is a single-chain plasma protein of mol. wt 92,400 containing 6.4% carbohydrate and it has serine as the amino terminal residue. Primary sequence analysis failed to provide evidence of homology between these two proteins.

摘要

人补体成分C6和C7已被纯化并进行了特性鉴定。成分C6是一种单链血浆蛋白,分子量为104,800,含3.8%的碳水化合物,其氨基末端残基为丙氨酸。成分C7是一种单链血浆蛋白,分子量为92,400,含6.4%的碳水化合物,其氨基末端残基为丝氨酸。一级序列分析未能提供这两种蛋白质之间存在同源性的证据。

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