Kirmani N, Tuazon C U, Geelhoed G W
Arch Intern Med. 1980 Feb;140(2):277-8. doi: 10.1001/archinte.140.2.277.
A 62-year-old woman with chronic active hepatitis receiving immunosuppressive drugs was initially admitted with sepsis secondary to an intra-abdominal abscess caused by Klebsiella pneumoniae. She had a stormy course despite adequate antimicrobial therapy. Her postoperative course was further complicated by a fungal infection. Blood, urine, and sputum cultures were positive for Trichosporon. Antifungal therapy was given but her condition deteriorated and she died. At autopsy, a disseminated fungal infection was found. Diagnosis and management of such infections in the immunosuppressed host are difficult.
一名62岁患有慢性活动性肝炎且正在接受免疫抑制药物治疗的女性，最初因肺炎克雷伯菌引起的腹腔内脓肿继发败血症而入院。尽管给予了充分的抗菌治疗，但她的病情仍很凶险。她术后又并发了真菌感染。血液、尿液和痰液培养曲霉菌均呈阳性。给予了抗真菌治疗，但她的病情仍恶化并最终死亡。尸检发现有播散性真菌感染。在免疫抑制宿主中诊断和处理此类感染很困难。
