Bailey D N, Guba J J
J Anal Toxicol. 1980 Nov-Dec;4(6):311-3. doi: 10.1093/jat/4.6.311.
Following intraperitoneal injection of phencyclidine in the rat, concentrations ranged from 148 to 1364 ng/mL in saliva (mean +/- SD, 567 +/- 415) and from 196 to 1016 ng/mL in corresponding serum samples (mean +/- SD, 502 +/- 231). Phencyclidine concentrations in saliva showed no significant correlation with those in serum, and saliva concentrations were occasionally higher than serum concentrations. The saliva:serum concentration ratios ranged from 0.4 to 3.0. Since hypersalivation is common in man and animals after phencyclidine ingestion, measurement of the compound in saliva may provide a useful alternative to serum and urine which are not always available for analysis.
给大鼠腹腔注射苯环利定后，唾液中苯环利定浓度范围为148至1364纳克/毫升（均值±标准差，567±415），相应血清样本中的浓度范围为196至1016纳克/毫升（均值±标准差，502±231）。唾液中苯环利定浓度与血清中的浓度无显著相关性，且唾液浓度偶尔高于血清浓度。唾液与血清浓度比范围为0.4至3.0。由于人及动物摄入苯环利定后常出现唾液分泌过多，检测唾液中的该化合物可能为血清和尿液检测提供一种有用的替代方法，因为血清和尿液并非总是可用于分析。
