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乙醇空间厌恶条件反射

Spatial aversion conditioning with ethanol.

作者信息

Cunningham C L

出版信息

Pharmacol Biochem Behav. 1981 Feb;14(2):263-4. doi: 10.1016/0091-3057(81)90255-0.

DOI:10.1016/0091-3057(81)90255-0
PMID:7208566
Abstract

To determine whether dose level affected ethanol's ability to establish a preference or aversion for an associated spatial location, two groups of male albino rats each received five pairings of an IP injection of ethanol (1 or 2 g/kg) with exposure to a distinctive compartment for 15 min. On alternate days, each rat was exposed to a different compartment after a saline injection. A choice test indicated that aversions were established at both dose levels, and thus failed to confirm a previous report of conditioned location preference at the lower dose level.

摘要

为了确定剂量水平是否会影响乙醇对相关空间位置建立偏好或厌恶的能力,两组雄性白化大鼠分别接受了五次腹腔注射乙醇(1或2克/千克)并暴露于一个独特隔室15分钟的配对实验。在隔天,每只大鼠在注射生理盐水后暴露于不同的隔室。选择测试表明,两个剂量水平都建立了厌恶反应,因此未能证实之前关于较低剂量水平下条件性位置偏好的报告。

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