从嗜肺军团菌中分离出的一种高分子量抗原的超微结构定位及保护活性
Ultrastructural localization and protective activity of a high-molecular-weight antigen isolated from Legionella pneumophila.
作者信息
Elliott J A, Johnson W, Helms C M
出版信息
Infect Immun. 1981 Feb;31(2):822-4. doi: 10.1128/iai.31.2.822-824.1981.
Abstract
Immunoperoxidase labeling showed that the F-1 antigen of Legionella pneumophila is located on the bacterial cell surface. Protection against lethal intraperitoneal challenge with serogroup 1 L. pneumophila was induced in guinea pigs by heat-killed cells and F-1 antigen from serogroup 1, but not by heat-killed cells or F-1 antigens from serogroup 2, 3, or 4.
摘要
免疫过氧化物酶标记显示，嗜肺军团菌的F-1抗原位于细菌细胞表面。用血清1型嗜肺军团菌的热灭活细胞和F-1抗原可诱导豚鼠对血清1型嗜肺军团菌致死性腹腔攻击产生保护作用，但血清2、3或4型的热灭活细胞或F-1抗原则不能。
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