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肾衰竭时血清肌红蛋白升高(作者译)

[Elevated serum myoglobin in renal failure (author's transl)].

作者信息

Kaiser H, Rumpf K W, Nordbeck H, Schrader J, Spaar U, Scheler F, Kreuzer H

出版信息

Klin Wochenschr. 1981 Mar 2;59(5):247-8. doi: 10.1007/BF01476583.

Abstract

In 44 patients with chronic renal failure of varied etiology serum immunoreactive myoglobin was measured and compared to values obtained in patients with normal renal function. Irrespective of the underlying disease a highly significant linear correlation was found between serum immunoreactive myoglobin and serum creatinine concentration. In patients with serum creatinine concentrations above 550 mu mol/1 (6.2 mg%) serum myoglobin was as a rule elevated above the range found in the controls with normal renal function. This was also true in dialysis patients. These result demonstrate that serum myoglobin may only be used with restrictions in the diagnosis of myocardial infarction in patients suffering from advanced chronic renal failure.

摘要

对44例病因各异的慢性肾衰竭患者测定了血清免疫反应性肌红蛋白,并与肾功能正常患者的测定值进行比较。无论潜在疾病如何,血清免疫反应性肌红蛋白与血清肌酐浓度之间均存在高度显著的线性相关性。血清肌酐浓度高于550μmol/1(6.2mg%)的患者,其血清肌红蛋白通常高于肾功能正常的对照组。透析患者也是如此。这些结果表明,在晚期慢性肾衰竭患者的心肌梗死诊断中,血清肌红蛋白的应用可能受到限制。

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