Katz A S, Michelson E L, Stawicki J, Holford F D
Arch Intern Med. 1981 Apr;141(5):603-6.
To evaluate the occurrence of ECG abnormalities during fiberoptic bronchoscopy in relation to specific stages of the procedure and to hypoxemia, we prospectively studied 50 hospitalized patients aged 53 +/- 18 years (mean +/- SD) who were undergoing bronchoscopy by continuously monitoring cardiac rhythm with a continuous two-channel ECG recorder and oxygen saturation by using ear oximetry. Major disturbances of cardiac rhythm (ie, atrial, ventricular, or both) developed in 20 (40%) patients. Ventricular arrhythmias were recorded in ten patients (20%) and occurred with greatest frequency during passage of the bronchoscope through the vocal cords in five of these patients. Atrial arrhythmias were detected in 16 patients (32%), but their occurrence did not correlate closely with any one stage of the procedure. Arrhythmias were most frequent in association with periods of maximum oxygen desaturation in 12 of these 20 patients. Oxygen desaturation persisted for greater than one hour after bronchoscopy in 34 (68%) of 50 subjects. Notably, no correlation was observed between the frequency of arrhythmias during bronchoscopy and patients' age, sex, prior medications, or preexisting cardiac or pulmonary disorders. In no case was an ECG abnormality associated with adverse clinical sequelae.
为了评估纤维支气管镜检查过程中心电图异常的发生情况与该操作的特定阶段及低氧血症的关系,我们对50例年龄为53±18岁(均值±标准差)的住院患者进行了前瞻性研究,这些患者正在接受支气管镜检查,通过连续双通道心电图记录仪持续监测心律,并使用耳部血氧饱和度仪监测血氧饱和度。20例(40%)患者出现了主要的心律紊乱(即心房、心室或两者皆有)。10例患者(20%)记录到室性心律失常,其中5例患者在支气管镜通过声带时发生率最高。16例患者(32%)检测到房性心律失常,但其发生与该操作的任何一个阶段均无密切关联。在这20例患者中的12例中,心律失常最常与最大程度的氧饱和度降低期相关。50例受试者中有34例(68%)在支气管镜检查后氧饱和度降低持续超过1小时。值得注意的是,支气管镜检查期间心律失常的频率与患者的年龄、性别、既往用药情况或既往存在的心脏或肺部疾病之间未观察到相关性。在任何情况下,心电图异常均未伴有不良临床后果。