脱氧胞嘧啶磷酸鸟嘌呤（CpG）与三联吡啶铂化合物之间的双螺旋DNA片段嵌入剂复合物的分子结构。
Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound.
作者信息
Wang A H, Nathans J, van der Marel G, van Boom J H, Rich A
出版信息
Nature. 1978 Nov 30;276(5687):471-4. doi: 10.1038/276471a0.
DOI:10.1038/276471a0
PMID:723928
Abstract
The crystal structure of a complex containing deoxy CpG and a terpyridine platinum compound (TPH) shows a DNA double helical fragment with TPH intercalated between two Watson-Crick GC base pairs. The DNA unwinding angle is 23 degrees and the pucker of the deoxyribose rings differ at the 3' and 5' ends.
摘要
一种包含脱氧CpG和三联吡啶铂化合物（TPH）的复合物的晶体结构显示，有一个DNA双螺旋片段，TPH插入在两个沃森-克里克GC碱基对之间。DNA解旋角为23度，脱氧核糖环在3'和5'端的皱折不同。
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