红细胞膜粘弹性恢复的温度依赖性

Temperature dependence of the viscoelastic recovery of red cell membrane.

作者信息

Hochmuth R M, Buxbaum K L, Evans E A

出版信息

Biophys J. 1980 Jan;29(1):177-82. doi: 10.1016/S0006-3495(80)85124-1.

DOI:10.1016/S0006-3495(80)85124-1

PMID:7260246

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1328668/

Abstract

The time-dependent recovery of an elongated red cell is studied as a function of temperature. Before release, the elongated cell is in static equilibrium where external forces are balanced by surface elastic force resultants. Upon release, the cell recovers its initial shape with a time-dependent exponential behavior characteristic of a viscoelastic solid material undergoing large ("finite") deformation. The recovery process is characterized by a time constant, tc, that decreases from approximately 0.27 s at 6 degrees C to 0.06 s at 37 degrees C. From this measurement of the time constant and an independent measurement of the shear modulus of surface elasticity for red cell membrane, the value for the membrane surface viscosity as a function of temperature can be calculated.

摘要

研究了拉长红细胞随时间的恢复情况，并将其作为温度的函数进行研究。在释放之前，拉长的细胞处于静态平衡状态，外力由表面弹性力合力平衡。释放后，细胞以随时间变化的指数行为恢复其初始形状，这种行为是经历大（“有限”）变形的粘弹性固体材料的特征。恢复过程的特征是时间常数(t_c)，它从6摄氏度时的约0.27秒降至37摄氏度时的0.06秒。根据这个时间常数的测量以及对红细胞膜表面弹性剪切模量的独立测量，可以计算出膜表面粘度随温度的函数值。