Pass H L, Salzman L F, Klorman R, Kaskey G B, Klein R H
Biol Psychiatry. 1978 Oct;13(5):587-93.
To examine the nature of impaired smooth pursuit eye movement (SPEM) in schizophrenia, 16 hospitalized schizophrenics in the acute phase and 16 hospitalized nonpsychotic patients were studied. The experiment consisted of five 30-sec visual tracking phases: (i) base line (no distraction); (ii) auditory-visual distraction; (iii) middle base line; (iv) dichotic listening; and (v) final base line. Schizophrenics were characterized by significantly more velocity arrests throughout all phases of the experiment. Auditory-visual distraction did not impair either group's SPEM relative to base line performance. In contrast, dichotic listening significantly increased both groups' velocity arrests. This form of distraction also tended to produce greater impairment among schizophrenics. The failure of apparently intense auditory-visual distraction to significantly disrupt schizophrenics' SPEM suggests that inattentiveness alone does not account for schizophrenics' tracking impairment. This notion is supported by the finding that only the more intense distraction by dichotic listening produced a (trend toward) greater impairment in schizophrenics.
为研究精神分裂症患者平滑跟踪眼动（SPEM）受损的本质，对16例急性期住院精神分裂症患者和16例住院非精神病患者进行了研究。实验包括五个30秒的视觉跟踪阶段：（i）基线期（无干扰）；（ii）视听干扰期；（iii）中间基线期；（iv）双耳分听期；（v）最终基线期。精神分裂症患者的特点是在实验的所有阶段中速度骤停显著更多。与基线表现相比，视听干扰并未损害两组的SPEM。相反，双耳分听显著增加了两组的速度骤停。这种干扰形式在精神分裂症患者中也往往会产生更大的损害。明显强烈的视听干扰未能显著破坏精神分裂症患者的SPEM，这表明仅注意力不集中并不能解释精神分裂症患者的跟踪障碍。这一观点得到以下发现的支持：只有更强烈的双耳分听干扰才会在精神分裂症患者中产生（趋于）更大的损害。
