Morley J E, Levine A S, Silvis S E
Science. 1981 Nov 6;214(4521):671-3. doi: 10.1126/science.7292006.
Parenteral and intracerebroventricular administration of calcitonin in rats resulted in the suppression of gastric acid secretion. This suppression also occurred in rats with insulin-induced hypoglycemia and after the administration of thyrotropin-releasing hormone. Intracerebroventricularly administered calcitonin was 1000 times more effective than parenterally administered calcitonin in suppressing gastric acid secretion. Calcitonin also inhibited the development of stress-induced ulcers in rats.
对大鼠进行降钙素的肠胃外和脑室内给药会导致胃酸分泌受到抑制。在胰岛素诱导的低血糖大鼠以及注射促甲状腺激素释放激素后，这种抑制作用同样会出现。在抑制胃酸分泌方面，脑室内注射的降钙素比肠胃外注射的降钙素有效1000倍。降钙素还能抑制大鼠应激性溃疡的形成。
