Levine A S, Morley J E
Brain Res. 1981 Oct 5;222(1):187-91. doi: 10.1016/0006-8993(81)90957-4.
Administration of parenteral and intracerebroventricular calcitonin resulted in suppression of stress-induced and spontaneous eating in rats. Calcitonin also reversed calcium chloride-induced eating and reduced 45Ca2+-uptake in a hypothalamic explant system. The mechanism of calcitonin-induced food suppression may be related to an alteration in calcium flux by neuronal tissue.
肠胃外和脑室内注射降钙素会抑制大鼠应激诱导和自发的进食行为。降钙素还能逆转氯化钙诱导的进食,并减少下丘脑外植体系统中45Ca2+的摄取。降钙素诱导食物抑制的机制可能与神经组织钙通量的改变有关。