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降钙素对大鼠进食的抑制作用。

Reduction of feeding in rats by calcitonin.

作者信息

Levine A S, Morley J E

出版信息

Brain Res. 1981 Oct 5;222(1):187-91. doi: 10.1016/0006-8993(81)90957-4.

DOI:10.1016/0006-8993(81)90957-4
PMID:7296266
Abstract

Administration of parenteral and intracerebroventricular calcitonin resulted in suppression of stress-induced and spontaneous eating in rats. Calcitonin also reversed calcium chloride-induced eating and reduced 45Ca2+-uptake in a hypothalamic explant system. The mechanism of calcitonin-induced food suppression may be related to an alteration in calcium flux by neuronal tissue.

摘要

肠胃外和脑室内注射降钙素会抑制大鼠应激诱导和自发的进食行为。降钙素还能逆转氯化钙诱导的进食,并减少下丘脑外植体系统中45Ca2+的摄取。降钙素诱导食物抑制的机制可能与神经组织钙通量的改变有关。

相似文献

1
Reduction of feeding in rats by calcitonin.降钙素对大鼠进食的抑制作用。
Brain Res. 1981 Oct 5;222(1):187-91. doi: 10.1016/0006-8993(81)90957-4.
2
Intraventricular calcitonin inhibits gastric acid secretion.脑室内降钙素抑制胃酸分泌。
Science. 1981 Nov 6;214(4521):671-3. doi: 10.1126/science.7292006.
3
Calcitonin as a feeding suppressant: localization of central action to the cerebral III ventricle.
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Intracerebroventricular injection of 125I-salmon calcitonin in rats: fate, anorexia and hypocalcemia.大鼠脑室内注射125I-鲑鱼降钙素:去向、厌食及低钙血症
Jpn J Pharmacol. 1985 Jan;37(1):21-9. doi: 10.1254/jjp.37.21.
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Calcitonin gene-related peptide mimics calcitonin actions in brain on growth hormone release and feeding.降钙素基因相关肽在大脑中模拟降钙素对生长激素释放和进食的作用。
Endocrinology. 1985 Jun;116(6):2685-7. doi: 10.1210/endo-116-6-2685.
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Muscimol induced feeding: a model to study the hypothalamic regulation of appetite.蝇蕈醇诱导进食:一种研究下丘脑食欲调节的模型。
Life Sci. 1981 Sep 21;29(12):1213-8. doi: 10.1016/0024-3205(81)90225-3.
7
Central administration of aminoprocalcitonin inhibits food intake and stimulates the hypothalamic-pituitary-adrenal axis in rats via the corticotrophin-releasing factor system.氨基末端脑钠肽前体的中枢给药通过促肾上腺皮质激素释放因子系统抑制大鼠摄食并刺激下丘脑-垂体-肾上腺轴。
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[Effect of picomolar intracerebroventricular administration of calcitonin on intestinal motility in the rat (author's transl)].
C R Seances Acad Sci III. 1982 May 10;294(17):881-6.
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Relationships between hypocalcaemic and anorectic effect of calcitonin in the rat.大鼠体内降钙素的低钙血症效应与厌食效应之间的关系。
Pharmacol Res Commun. 1985 Mar;17(3):209-15. doi: 10.1016/0031-6989(85)90095-5.
10
Calcitonin: inhibitory effect on eating in rats.降钙素:对大鼠进食的抑制作用。
Science. 1979 Nov 16;206(4420):850-2. doi: 10.1126/science.493987.

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Calcitonin and bipolar disorder: a hypothesis revisited.降钙素与双相情感障碍:再探一种假说
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3
Cold-restraint- and TRH-induced ulcer models demonstrate different biochemical and morphological manifestations in gastric and hepatic tissues in rats. Role of calcitonin.
冷束缚和促甲状腺激素释放激素诱导的溃疡模型显示大鼠胃和肝组织中不同的生化和形态学表现。降钙素的作用。
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A step towards developing the expertise to control hunger and satiety: regulatory role of satiomem--a membrane proteoglycan.迈向掌握控制饥饿与饱腹感专业技能的一步:饱腹感素膜蛋白聚糖(satiomem)的调节作用
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Satietin, a blood-borne anorectic glycoprotein, as the putative rate-limiting satiety signal in the negative feed-back of food intake.饱腹感素是一种通过血液传播的厌食性糖蛋白,被认为是食物摄入负反馈中假定的限速饱腹感信号。
Z Ernahrungswiss. 1984 Jun;23(2):85-103. doi: 10.1007/BF02021684.
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Parathyrin and calcitonin stimulate cyclic AMP accumulation in cultured murine brain cells.甲状旁腺素和降钙素刺激培养的鼠脑细胞中环状AMP的积累。
EMBO J. 1982;1(3):297-302. doi: 10.1002/j.1460-2075.1982.tb01163.x.
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J Endocrinol Invest. 1985 Oct;8(5):409-15. doi: 10.1007/BF03348525.
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Appetite regulation: the role of peptides and hormones.食欲调节:肽类和激素的作用
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