Sakuta S
Stroke. 1981 Nov-Dec;12(6):824-8. doi: 10.1161/01.str.12.6.824.
Erythrocyte deformability was determined in 48 patients with cerebrovascular disease and 116 healthy controls as an index of blood filtrability in microcirculation. Hemo-rheological and blood chemical changes were also studied to assess their effect on filtrability. Erythrocyte deformability, determined by Reid's method, was expressed as the deformability index (DI). DI and ATP levels decreased with advancing age in controls and patients; these levels were lower in patients. In the controls, DI was inversely proportional to hematocrit, hemoglobin, fibrinogen, and lactate; in patients, it was directly proportional to albumin. There were no significant differences in DI and ATP levels in patients with cerebral infarction and cerebral hemorrhage. The values for DI and ATP levels were the same in arterial and venous blood.
对48例脑血管疾病患者和116名健康对照者进行红细胞变形性测定，以此作为微循环血液滤过性的指标。还研究了血液流变学和血液化学变化，以评估它们对滤过性的影响。采用里德方法测定的红细胞变形性以变形性指数（DI）表示。在对照者和患者中，DI和ATP水平均随年龄增长而降低；患者的这些水平更低。在对照者中，DI与血细胞比容、血红蛋白、纤维蛋白原和乳酸呈负相关；在患者中，DI与白蛋白呈正相关。脑梗死和脑出血患者的DI和ATP水平无显著差异。动脉血和静脉血的DI和ATP水平值相同。
