Pai C H, Mors V, Toma S
Infect Immun. 1978 Nov;22(2):334-8. doi: 10.1128/iai.22.2.334-338.1978.
A total of 414 cultures of Yersinia enterocolitica isolated from human and nonhuman sources were examined for heat-stable enterotoxin (ST) production to determine whether enterotoxigenicity was related to the source of isolation, serotype, or biochemical characteristics of the organism. A total of 65% of all cultures were found to produce ST. Enterotoxin production was much more prevalent in strains isolated from humans (218/232) than in those isolated from animals (17/34), water (9/49), raw milk (14/44), and food (10/55). Strains belonging to the serotypes O:3; 8; 5,27; 6,30; 9, often isolated from human infections, were almost always enterotoxigenic (191/196), although ST production was also highly prevalent among a few other serotypes. The most significant difference was observed between the groups that differed in the ability to ferment rhamnose; only 13 of 130 rhamnose-positive isolates produced ST (10%) compared to 255 of 284 rhamnose-negative cultures (90%). These results suggest that ST production is ubiquitous in Y. enterocolitica, with the highest prevalence among strains associated with human infections.
对从人类和非人类来源分离出的414株小肠结肠炎耶尔森菌培养物进行了耐热肠毒素（ST）产生情况的检测，以确定产肠毒素性是否与分离源、血清型或该生物体的生化特性有关。结果发现，所有培养物中有65%能产生ST。从人类分离出的菌株（218/232）中产肠毒素的情况比从动物（17/34）、水（9/49）、生牛奶（14/44）和食物（10/55）中分离出的菌株更为普遍。属于血清型O:3、8、5,27、6,30、9的菌株，常从人类感染中分离得到，几乎总是产肠毒素的（191/196），不过在其他一些血清型中ST产生也很普遍。在发酵鼠李糖能力不同的组之间观察到最显著的差异；130株鼠李糖阳性分离株中只有13株（10%）产生ST，而284株鼠李糖阴性培养物中有255株（90%）产生ST。这些结果表明，ST产生在小肠结肠炎耶尔森菌中普遍存在，在与人类感染相关的菌株中发生率最高。
