源自巴尔的摩纵向研究参与者的皮肤成纤维细胞培养物：细胞衰老研究的新资源。

Skin fibroblast cultures derived from members of the Baltimore longitudinal study: a new resource for studies of cellular aging.

作者信息

Schneider E L, Monticone R, Smith J, Braunschweiger K, Roberts T

出版信息

Cytogenet Cell Genet. 1981;31(2):40-6. doi: 10.1159/000131624.

Abstract

Approximately 100 human fibroblast-like cell lines derived from the upper arms of members of the Baltimore Longitudinal Study have been deposited in the Aging Cell Bank at the Institute for Medical Research, Camden, N.J. These cell lines were derived from individuals ranging from 29 to 96 years in age. The in vitro lifespan of each culture has been estimated by the distribution of colony sizes. The availability of cell lines of known proliferative potential from donors of various ages should provide an important new resource for cellular aging studies.

摘要

大约100个人类成纤维细胞样细胞系取自巴尔的摩纵向研究项目参与者的上臂，已存入新泽西州卡姆登市医学研究所的衰老细胞库。这些细胞系来自年龄在29岁至96岁之间的个体。每种培养物的体外寿命已通过集落大小分布进行了估计。来自不同年龄供体的具有已知增殖潜力的细胞系的可得性应为细胞衰老研究提供重要的新资源。