Brook I, Altman R S, Loebman W W, Seeff L B
Dig Dis Sci. 1981 Dec;26(12):1089-94. doi: 10.1007/BF01295973.
Lactate concentrations were measured in the ascitic fluid of patients using the Monotest Lactate Kit, an inexpensive, reliable bedside test that gives results within 15 min. The values were significantly higher in 24 patients with proven bacterial peritonitis, eight of them with spontaneous bacterial peritonitis, than in 53 patients with uninfected ascites of various other etiologies. In only two patients from the latter group, both with hepatic carcinoma and peritoneal metastases, were the values in the range found in bacterial peritonitis. Lactate determination was at least as sensitive as measurement of WBC levels for diagnosing peritonitis. Serial determinations in two patients with peritonitis showed declining values as the disease responded to treatment. The test has particular relevance for patients with spontaneous bacterial peritonitis, because this disease, which is potentially life-threatening although frequently asymptomatic, requires immediate treatment, yet currently depends on time-consuming culture procedures for diagnosis.
使用Monotest乳酸试剂盒测量患者腹水的乳酸浓度，该试剂盒价格低廉、可靠，是一种可在15分钟内得出结果的床旁检测方法。24例确诊为细菌性腹膜炎的患者（其中8例为自发性细菌性腹膜炎）的乳酸浓度值显著高于53例其他病因引起的未感染腹水患者。后一组中只有2例患有肝癌和腹膜转移的患者，其乳酸浓度值在细菌性腹膜炎的范围内。乳酸测定在诊断腹膜炎方面至少与白细胞水平测量一样敏感。两名腹膜炎患者的连续测定结果显示，随着疾病对治疗产生反应，乳酸浓度值下降。该检测对自发性细菌性腹膜炎患者尤为重要，因为这种疾病虽然通常无症状，但可能危及生命，需要立即治疗，而目前其诊断依赖于耗时的培养程序。
