Isawa T, Teshima T, Hirano T, Ebina A, Shiraishi K, Fukuda Y, Konno K
Tohoku J Exp Med. 1981 May;134(1):71-7. doi: 10.1620/tjem.134.71.
Dopamine effect on regional pulmonary perfusion in the right upper lobe was studied in 6 dogs in which the lobe was isolated by a balloon catheter and artificially ventilated with nitrogen, air or 60% oxygen in nitrogen, while the rest of the lungs was allowed spontaneous air respiration. Dopamine was administered at the rate of 20 micrograms/kg/min. Each dog served as its own control. There was no change in the regional vascular responses to the different alveolar oxygen tensions in the right upper lobe before and after dopamine administration.
在6只犬中研究了多巴胺对右上叶局部肺灌注的影响。在这些犬中，用球囊导管将右上叶隔离，并用氮气、空气或氮气中60%的氧气进行人工通气，而其余肺组织则进行自主呼吸。多巴胺以20微克/千克/分钟的速率给药。每只犬均作为自身对照。给药前后，右上叶对不同肺泡氧张力的局部血管反应无变化。
