Gebhardt C, Stolte M
Langenbecks Arch Chir. 1978 Oct 16;346(3):149-66. doi: 10.1007/BF01261238.
The effect of the occlusion of the pancreatic duct system with a new alcoholic solution of amino acids has been studied in animal experiments. The solution becomes solid in the duct system, is microbiologically indifferent and becomes disintegrated within 11 days. This time, however, is sufficient to keep a high-grade atrophy of the exocrine parenchyma. With this method one doesn't risk the provocation of an acute pancreatitis. The development of fistulas following exploratory excision is prevented by the filling of the duct system. The solution could be qualified for a therapeutical acceleration of the "burning-out" of the chronic pancreatitis.
在动物实验中,研究了一种新的氨基酸酒精溶液阻塞胰腺导管系统的效果。该溶液在导管系统中会固化,无微生物活性,并在11天内分解。然而,这段时间足以使外分泌实质发生高度萎缩。用这种方法不会有引发急性胰腺炎的风险。通过填充导管系统可防止探查性切除后瘘管的形成。该溶液有望在治疗上加速慢性胰腺炎的“消退”。