金黄色葡萄球菌中庆大霉素C的新型质粒介导磷酸化作用

New plasmid-mediated phosphorylation of gentamicin C in Staphylococcus aureus.

作者信息

Kawabe H, Naganawa H, Kondo S, Umezawa H, Mitsuhashi S

出版信息

Microbiol Immunol. 1978;22(9):515-21. doi: 10.1111/j.1348-0421.1978.tb00399.x.

DOI:10.1111/j.1348-0421.1978.tb00399.x

Abstract

A clinical isolate of Staphylococcus aureus resistant to gentamicin, kanamycin and 3',4'-dideoxykanamycin B contained two enzymes capable of inactivating gentamicin, i.e., an aminoglycoside 2''-phosphotransferase and aminoglycoside acetyltransferase.

摘要

一株对庆大霉素、卡那霉素和3',4'-二脱氧卡那霉素B耐药的金黄色葡萄球菌临床分离株含有两种能够使庆大霉素失活的酶，即一种氨基糖苷2''-磷酸转移酶和氨基糖苷乙酰转移酶。