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耐庆大霉素葡萄球菌:皮肤科一次暴发的遗传学研究

Gentamicin-resistant staphylococci: genetics of an outbreak in a dermatology department.

作者信息

Naidoo J, Noble W C, Weissmann A, Dyke K G

出版信息

J Hyg (Lond). 1983 Aug;91(1):7-16. doi: 10.1017/s0022172400059970.

Abstract

The genetics of gentamicin resistance in Staphylococcus aureus strains isolated during an outbreak of infection in dermatology department have been studied. The predominant strain of S. aureus did not appear to possess a plasmid mediating gentamicin resistance though one isolate yielded a plasmid coding for penicillin and gentamicin. Three distinct plasmids were isolated from other phage types of S. aureus which appeared towards the end of the epidemic. There appeared to be a stepwise loss of gentamicin resistance in the predominant strain.

摘要

对皮肤科感染暴发期间分离出的金黄色葡萄球菌菌株中庆大霉素耐药性的遗传学进行了研究。金黄色葡萄球菌的优势菌株似乎不具有介导庆大霉素耐药性的质粒,尽管有一个分离株产生了编码青霉素和庆大霉素的质粒。从疫情后期出现的其他噬菌体类型的金黄色葡萄球菌中分离出了三种不同的质粒。优势菌株中庆大霉素耐药性似乎呈逐步丧失的趋势。

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