Melia R J, Florey C D, Chinn S
J Epidemiol Community Health. 1981 Sep;35(3):168-73. doi: 10.1136/jech.35.3.168.
A study was set up to investigate the effects of annual changes in the levels of atmospheric smoke and SO2 on changes in health from 1973 to 1977 in primary schoolchildren from 28 randomly selected areas of England and Scotland. Changes in health were measured by taking the change in number of respiratory conditions reported from one annual examination to the next. The number of areas with data on pollution in each period was 5,9,17, and 14 respectively and within these areas the response rate varied from 65% to 74%. Altogether 857, 1436, 2702, and 2036 children respectively who were of white ethnic origin, aged 6 to 11, and had complete data on sex, social class, and changes in health were studied in each period. In 1973-4 the levels of pollution were highest and showed the greatest decline. The greatest annual mean change in smoke was a decrease from 71.9 to 50.5 microgram/m3 and in SO2 a decrease from 94.2 to 47.6 microgram/m3. However, no relation was found between improvement in health and decreasing levels of pollution. In subsequent years, when the levels of pollution were lower and showed smaller changes, change in health was also unrelated to changes in pollution. Thus no evidence was found to suggest that the levels measured during the study were harmful to health.
一项研究旨在调查1973年至1977年期间,英格兰和苏格兰28个随机选取地区的小学生中,大气烟雾和二氧化硫水平的年度变化对健康变化的影响。通过比较每年一次体检报告的呼吸道疾病数量变化来衡量健康状况的变化。每个时期有污染数据的地区数量分别为5个、9个、17个和14个,在这些地区,应答率从65%到74%不等。每个时期分别研究了857名、1436名、2702名和2036名白人儿童,他们年龄在6至11岁之间,有完整的性别、社会阶层和健康变化数据。1973 - 1974年污染水平最高,下降幅度也最大。烟雾的年平均最大变化是从71.9微克/立方米降至50.5微克/立方米,二氧化硫从94.2微克/立方米降至47.6微克/立方米。然而,未发现健康状况改善与污染水平下降之间存在关联。在随后几年,当污染水平较低且变化较小时,健康变化也与污染变化无关。因此,没有证据表明研究期间测量的污染水平对健康有害。