Korn E L, Whittemore A S
Biometrics. 1979 Dec;35(4):795-802.
New methods are presented for analyzing repeated binary health measurements of individuals exposed to varying levels of air pollution. The methods involve a separate logistic regression of response against environmental covariates for each individual. Parameters reflecting individual susceptibility to pollutants and weather are estimated using Cox's regression techniques (1970, 1972a). The individual parameters are combined to yield summary estimates of environmental effects. The approach does not require independence of successive health measurements. It is illustrated with data on asthma and air pollution in the Los Angeles area.
本文提出了新的方法,用于分析暴露于不同空气污染水平下个体的重复二元健康测量数据。这些方法包括对每个个体的反应与环境协变量进行单独的逻辑回归。使用Cox回归技术(1970年,1972a)估计反映个体对污染物和天气易感性的参数。将个体参数合并以得出环境影响的汇总估计值。该方法不需要连续健康测量数据具有独立性。文中以洛杉矶地区哮喘与空气污染的数据为例进行了说明。