MacSearraigh E T, Doyle C T, Twomey M, O'Sullivan D J
Postgrad Med J. 1978 Aug;54(634):528-32. doi: 10.1136/pgmj.54.634.528.
Nine of ninety patients with sarcoidosis were found to have significant renal impairment. Epithelioid granulomata were present in five of eight patients who had renal biopsies and glomerular lesions were present in six. There was close correlation between hypercalcaemia, hyperuricaemia, nephrocalcinosis and creatinine clearance. In one patient, renal sarcoidosis complicated membrano-proliferative glomerulonephritis and one patient died in end-stage renal disease.
90例结节病患者中有9例被发现存在明显的肾功能损害。在接受肾活检的8例患者中,有5例存在上皮样肉芽肿,6例存在肾小球病变。高钙血症、高尿酸血症、肾钙质沉着症与肌酐清除率之间存在密切相关性。1例患者的肾结节病并发膜增生性肾小球肾炎,1例患者死于终末期肾病。