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一名感染乙型肝炎的心脏外科医生将乙肝表面抗原(HBsAg)传播给了四名患者,导致他们出现慢性抗原血症。

HBsAG transmission from a cardiac surgeon incubating hepatitis B resulting in chronic antigenemia in four patients.

作者信息

Haerem J W, Siebke J C, Ulstrup J, Geiran O, Helle I

出版信息

Acta Med Scand. 1981;210(5):389-92. doi: 10.1111/j.0954-6820.1981.tb09836.x.

Abstract

A cardiac surgeon experienced an uneventful course of acute hepatitis B. HBsAg was transmitted to 11 persons: 5 of 72 patients operated on during his incubation of hepatitis B, three relatives of the infected patients, one laboratory technician, and two of the surgeon's family members. Two years later, 4 of the 5 operated patients are still infectious, whereas the 7 non-operated persons have cleared their antigenemia. This study demonstrates the significant risk of hepatitis B transmission from a cardiac surgeon incubating the disease. Furthermore, it indicates that patients who have been infected during open heart surgery and cardiopulmonary bypass run a particular risk of becoming chronic HBs antigen carriers.

摘要

一位心脏外科医生经历了一次无并发症的急性乙型肝炎病程。乙肝表面抗原(HBsAg)传播给了11个人:在他患乙型肝炎潜伏期接受手术的72名患者中的5名、受感染患者的3名亲属、1名实验室技术员以及这位外科医生的2名家庭成员。两年后,5名接受手术的患者中有4名仍具有传染性,而7名未接受手术的人已清除了抗原血症。这项研究表明,处于疾病潜伏期的心脏外科医生传播乙型肝炎的风险很大。此外,它还表明,在心脏直视手术和体外循环期间被感染的患者有成为慢性乙肝表面抗原携带者的特殊风险。

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