Babbott F L, Gump D W, Sylwester D L, MacPherson B V, Holly R C
Am J Public Health. 1980 Mar;70(3):241-5. doi: 10.2105/ajph.70.3.241.
This study reviews the respiratory status of a sample of Vermont male dairy farmers, and a comparison group from industry, matched for age, sex and smoking. Survey instruments included a standardized questionnaire and simple pulmonary function tests. In general, past and present smokers had more respiratory symptoms than never-smokers; and farmers, in all smoking categories, reported symptoms with greater frequency than did their counterparts from industry. Forced vital capacity (FVC) tended to be lower among men with a history of smoking but, within each smoking category, dairymen and factory workers had very similar FVCs. Farmers who had never smoked or who were current cigarette users had lower FEV1/FVC (forced expiratory volume at one second/forced vital capacity) ratios than their controls from industry. Sixteen diarymen demonstrated precipitins to either Micropolyspora faeni (13) or Thermoactinomyces vulgaris, (3), but only one reported a constellation of symptoms compatible with farmer's lung disease. The estimated prevalence of antibodies to thermophilic actinomyces in this farm population was approximately 10 per cent. Although sample sizes were limited, dairymen from small farms tended to be older, have more respiratory symptoms, less satisfactory pulmonary function, and more serologic evidence of exposure to farmer's lung antigens than their counterparts from large farms.
本研究回顾了佛蒙特州男性奶农样本以及来自工业领域的对照组（在年龄、性别和吸烟情况方面相匹配）的呼吸状况。调查工具包括一份标准化问卷和简单的肺功能测试。总体而言，过去和现在的吸烟者比从不吸烟者有更多的呼吸道症状；并且在所有吸烟类别中，奶农报告症状的频率高于来自工业领域的同行。有吸烟史的男性的用力肺活量（FVC）往往较低，但在每个吸烟类别中，奶农和工厂工人的FVC非常相似。从不吸烟或目前吸烟的奶农的第一秒用力呼气量/用力肺活量（FEV1/FVC）比值低于来自工业领域的对照组。16名奶农对嗜热放线菌（13人）或普通嗜热放线菌（3人）呈沉淀素阳性，但只有一人报告了与农民肺疾病相符的一系列症状。该农场人群中嗜热放线菌抗体的估计患病率约为10%。尽管样本量有限，但与大型农场的奶农相比，小型农场的奶农往往年龄更大，呼吸道症状更多，肺功能更差，且有更多接触农民肺抗原的血清学证据。
