Hirsch S R, Kalbfleisch J H
J Allergy Clin Immunol. 1980 Apr;65(4):274-7. doi: 10.1016/0091-6749(80)90155-4.
From an earlier study we proposed that the relative peripheral basophilia of subjects with symptomatic hay fever might be associated with a basophil chemotactic factor in the serum. Six subjects with symptomatic hay fever and six nonallergic subjects were tested for basophil chemotaxis (BC) weekly during and after the hay fever season. Cells of the allergic subjects with autologous serum showed significantly more BC than with control serum during the symptomatic weeks. After they hay fever season there was no difference in BC between the allergic and nonallergic groups. We conclude that there is a BC factor(s) in the serum of symptomatic subjects with hay fever which requires basophils from symptomatic subjects to be demonstrable.
根据一项早期研究，我们提出有症状性花粉症患者外周血嗜碱性粒细胞增多可能与血清中的嗜碱性粒细胞趋化因子有关。在花粉症季节期间及之后，对6名有症状性花粉症患者和6名非过敏患者每周进行嗜碱性粒细胞趋化性（BC）检测。在有症状的几周内，过敏患者的细胞与自身血清一起时显示出的BC明显多于与对照血清一起时。花粉症季节过后，过敏组和非过敏组之间的BC没有差异。我们得出结论，有症状性花粉症患者的血清中存在一种BC因子，该因子需要有症状患者的嗜碱性粒细胞才能被检测到。
