急性结肠炎中泼尼松龙的吸收情况。
Prednisolone absorption in acute colitis.
作者信息
Elliott P R, Powell-Tuck J, Gillespie P E, Laidlow J M, Lennard-Jones J E, English J, Chakraborty J, Marks V
出版信息
Gut. 1980 Jan;21(1):49-51. doi: 10.1136/gut.21.1.49.
Abstract
Peak plasma levels were reduced after an oral dose of 40 mg prednisolone in six patients with severe acute colitis as compared with six normal subjects, though total absorption appeared to be similar; the findings suggest that prednisolone absorption was delayed in acute colitis. A dilutional fall in plasma albumin was observed in normal subjects and in the patients after 40 mg prednisolone by mouth.
摘要
与六名正常受试者相比，六名重症急性结肠炎患者口服40毫克泼尼松龙后，血浆峰值水平降低，尽管总吸收似乎相似；研究结果表明，急性结肠炎患者泼尼松龙的吸收延迟。正常受试者和口服40毫克泼尼松龙后的患者均观察到血浆白蛋白稀释性下降。
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本文引用的文献
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Gut. 1969 Mar;10(3):194-7. doi: 10.1136/gut.10.3.194.
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A radioimmunoassay method for prednisolone: comparison with the competitive protein binding method.一种泼尼松龙的放射免疫分析方法：与竞争性蛋白结合法的比较。
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Variation in plasma prednisolone concentrations in renal transplant recipients given enteric-coated prednisolone.接受肠溶包衣泼尼松龙的肾移植受者血浆泼尼松龙浓度的变化
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