Bonnet M
University Eye Clinic, U.E.R. Lyon Nord, Hôpital de la Croix-Rousse, France.
Graefes Arch Clin Exp Ophthalmol. 1991;229(6):526-32. doi: 10.1007/BF00203315.
Between September 1972 and March 1989, we examined 25 eyes of 24 patients exhibiting optic nerve-head pits associated with serous macular detachment. We followed 21 patients for a period of 1-15 years (mean, 62 months). Various treatment modalities were applied, depending on the time of initial examination. Five eyes underwent no treatment and three eyes underwent two distinct treatment modalities. Photocoagulation treatment was performed in ten eyes. Argon laser photocoagulation was combined with intravitreal injection of pure SF6 in eight eyes and of C3F8 in three. Intravitreal injection of pure C3F8 without photocoagulation was carried out in two eyes. The results of biomicroscopy of the vitreous gel and of fluorescein angiography and the responses to the various treatment modalities support the hypothesis that the mechanism underlying serous macular detachment complicating optic nerve-head pits is traction retinal detachment combined with a rhegmatogenous component in the roof of the optic pit.
1972年9月至1989年3月期间，我们检查了24例患有与浆液性黄斑脱离相关的视神经乳头凹陷患者的25只眼睛。我们对21例患者进行了1至15年的随访（平均62个月）。根据初次检查时间采用了各种治疗方式。5只眼睛未接受治疗，3只眼睛接受了两种不同的治疗方式。10只眼睛接受了光凝治疗。8只眼睛采用氩激光光凝联合玻璃体内注射纯SF6，3只眼睛联合玻璃体内注射C3F8。2只眼睛未进行光凝仅进行了玻璃体内注射纯C3F8。玻璃体凝胶的生物显微镜检查结果、荧光素血管造影结果以及对各种治疗方式的反应支持了这样一种假说，即视神经乳头凹陷并发浆液性黄斑脱离的潜在机制是牵拉性视网膜脱离合并视神经凹陷顶部的孔源性成分。
