Benazet F, Cartier M, Florent J, Godard C, Jung G, Lunel J, Mancy D, Pascal C, Renaut J, Tarridec P, Theilleux J, Tissier R, Dubost M, Ninet L
Experientia. 1980 Apr 15;36(4):414-6. doi: 10.1007/BF01975121.
Nosiheptide (9671 R.P.) isolated from Streptomyces actuosus 40037 (NRRL 2954) is a sulfur-containing polypeptidic antibiotic, quite different from all the other members of this family. Very active in vitro against gram-positive bacteria, it is inactive in vivo in experimentally infected mice. Not toxic, even at high dose, it may be used as a feed additive for chickens and pigs and it shows a favourable effect on the growth and conversion index.
从活跃链霉菌40037(NRRL 2954)中分离出的诺西肽(9671 R.P.)是一种含硫多肽类抗生素,与该家族的所有其他成员有很大不同。它在体外对革兰氏阳性菌非常有效,但在实验感染的小鼠体内无活性。即使高剂量使用也无毒,可作为鸡和猪的饲料添加剂,对生长和转化率有良好影响。