附着于微孔膜的聚集免疫球蛋白对中性粒细胞迁移的抑制作用。
Inhibition of neutrophil migration by aggregated immunoglobulin attached to micropore membranes.
作者信息
Kemp A S, Brown S
出版信息
Immunology. 1980 Apr;39(4):529-34.
Abstract
The effect of substrate-bound immunoglobulin on neutrophil migration was examined. Immunoglobulin aggregates bound to micropore membranes inhibited the neutrophil response to a chemotactic stimulus. This inhibition was reversed by the presence of aggregates in suspension suggesting competition between substrate-bound and free aggregates for neutrophil surface binding sites. The immobilization of neutrophils by substrate-bound aggregated immunoglobulin suggests a mechanism for the accumulation of neutrophils at sites of immune complex deposition and tissue-bound antibodies in vivo.
摘要
研究了底物结合免疫球蛋白对中性粒细胞迁移的影响。结合在微孔膜上的免疫球蛋白聚集体抑制了中性粒细胞对趋化刺激的反应。悬浮液中聚集体的存在可逆转这种抑制作用，这表明底物结合聚集体与游离聚集体之间存在对中性粒细胞表面结合位点的竞争。底物结合的聚集免疫球蛋白使中性粒细胞固定，这提示了中性粒细胞在体内免疫复合物沉积部位和组织结合抗体部位积聚的一种机制。
相似文献
1
Inhibition of neutrophil migration by aggregated immunoglobulin attached to micropore membranes.附着于微孔膜的聚集免疫球蛋白对中性粒细胞迁移的抑制作用。
Immunology. 1980 Apr;39(4):529-34.
2
Inhibition of human neutrophil migration by aggregated gammaglobulin.聚合γ球蛋白对人中性粒细胞迁移的抑制作用。
Clin Exp Immunol. 1979 May;36(2):334-41.
3
Inhibition of neutrophil migration by sera from patients with rheumatoid arthritis.类风湿关节炎患者血清对中性粒细胞迁移的抑制作用。
Clin Exp Immunol. 1979 Jun;36(3):423-9.
4
The effect of salicylate on human leucocyte migration.水杨酸盐对人体白细胞迁移的影响。
Clin Exp Immunol. 1982 Jul;49(1):233-8.
5
Suppression of leucocyte chemokinesis and chemotaxis by human IgA.人IgA对白细胞趋化性和趋化作用的抑制
Clin Exp Immunol. 1980 May;40(2):388-95.
6
Effect of in vitro and in vivo migration of bovine neutrophils on binding and expression of Fc receptors for IgG2 and IgM.
Am J Vet Res. 1994 Feb;55(2):221-6.
7
Immunoglobulin A: Fc(alpha)RI interactions induce neutrophil migration through release of leukotriene B4.免疫球蛋白A：Fc(α)RI相互作用通过白三烯B4的释放诱导中性粒细胞迁移。
Gastroenterology. 2009 Dec;137(6):2018-29.e1-3. doi: 10.1053/j.gastro.2009.06.047. Epub 2009 Jun 23.
8
Inhibition of polymorphonuclear leucocyte locomotion by surface-bound antigen-antibody complexes.表面结合的抗原-抗体复合物对多形核白细胞运动的抑制作用。
Immunology. 1983 Jun;49(2):329-36.
9
[Effect of various chemotactic factors on migration and on the oxidative metabolism of human polymorphonuclear leukocytes].
Boll Soc Ital Biol Sper. 1977 Oct 30;53(20):1725-31.
10
Failure of neutrophil chemotactic function in breast cancer patients treated with chemotherapy.接受化疗的乳腺癌患者中性粒细胞趋化功能的衰竭
Cancer Chemother Pharmacol. 2006 May;57(5):663-70. doi: 10.1007/s00280-005-0086-4. Epub 2005 Aug 27.
引用本文的文献
1
Effects of human IgG on locomotion of human neutrophils related to IgG binding of a hydrophobic probe.人免疫球蛋白G（IgG）对人中性粒细胞运动的影响与疏水探针的IgG结合有关。
Immunology. 1980 Oct;41(2):457-66.
2
Inflammatory synovial tissue mononuclear cells release leucocyte migration inhibition factor in antigen- and mitogen-free cultures.炎症滑膜组织单核细胞在无抗原和无丝裂原的培养条件下释放白细胞迁移抑制因子。
Ann Rheum Dis. 1981 Aug;40(4):388-95. doi: 10.1136/ard.40.4.388.
3
Inhibition of polymorphonuclear leucocyte locomotion by surface-bound antigen-antibody complexes.表面结合的抗原-抗体复合物对多形核白细胞运动的抑制作用。
Immunology. 1983 Jun;49(2):329-36.
4
The effect of salicylate on human leucocyte migration.水杨酸盐对人体白细胞迁移的影响。
Clin Exp Immunol. 1982 Jul;49(1):233-8.
5
The degranulation response in differentiated HL-60 cells.分化的HL-60细胞中的脱颗粒反应。
Clin Exp Immunol. 1988 Dec;74(3):483-8.
6
Chemotactic properties of rat immunoglobulins and immune complexes.大鼠免疫球蛋白及免疫复合物的趋化特性。
Infect Immun. 1989 Feb;57(2):452-7. doi: 10.1128/iai.57.2.452-457.1989.
本文引用的文献
1
Haptotaxis and the mechanism of cell motility.趋触性与细胞运动机制。
Nature. 1967 Jan 21;213(5073):256-60. doi: 10.1038/213256a0.
2
3
4
Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor.白细胞移动与趋化性。评估及证明一种细胞源性趋化因子的新方法。
J Exp Med. 1973 Feb 1;137(2):387-410. doi: 10.1084/jem.137.2.387.
5
Analysis of individual leucocyte behavior during chemotaxis.趋化作用期间单个白细胞行为的分析。
Exp Cell Res. 1972 Jan;70(1):129-39. doi: 10.1016/0014-4827(72)90190-5.
6
Cell-substrate adhesivity. A determinant of cell motility.
Exp Cell Res. 1972 Jan;70(1):33-40. doi: 10.1016/0014-4827(72)90178-4.
7
Interaction of cells with immune complexes: adherence, release of constituents, and tissue injury.细胞与免疫复合物的相互作用：黏附、成分释放及组织损伤。
J Exp Med. 1971 Sep 1;134(3 Pt 2):114s-135s.
8
A proposal for the definition of terms related to locomotion of leucocytes and other cells.关于白细胞及其他细胞运动相关术语定义的提案。
Clin Exp Immunol. 1977 Mar;27(3):377-80.
9
Chemotaxis of neutrophil leukocytes towards substratum-bound protein attractants.
Exp Cell Res. 1978 Dec;117(2):403-12. doi: 10.1016/0014-4827(78)90153-2.
10
Separation and functional characterization of human neutrophil subpopulations.人类中性粒细胞亚群的分离与功能特性研究
Blood. 1978 Apr;51(4):659-69.
Zotero 插件