感染刚果锥虫和活跃锥虫的瘤牛的溶血补体和血清C3水平以及杀锥虫治疗的效果。
Hemolytic complement and serum C3 levels in Zebu cattle infected with Trypanosoma congolense and Trypanosoma vivax and the effect of trypanocidal treatment.
作者信息
Rurangirwa F R, Tabel H, Losos G, Tizard I R
出版信息
Infect Immun. 1980 Mar;27(3):832-6. doi: 10.1128/iai.27.3.832-836.1980.
Abstract
Total hemolytic complement and C3 levels were found to drop to 6.25% and 50% of preinfection levels, respectively, during trypanosome infections. Chemotherapeutic elimination of the trypanosomes with Berenil led to recovery of preinfection levels within 7 days and 11 days when cattle infected with Trypanosome congolense and Trypanosoma vivax, respectively, were treated 37 days after onset of infection. Recovery was slower in T. vivax-infected cattle treated on day 50. Berenil treatment had no effect on complement levels in control animals. The possible causes and implications of these low complement levels in bovine trypanosomiasis are discussed.
摘要
在锥虫感染期间，总溶血补体和C3水平分别降至感染前水平的6.25%和50%。当感染刚果锥虫和活泼锥虫的牛在感染开始37天后分别用贝尼尔进行化疗清除锥虫时，感染刚果锥虫的牛在7天内恢复到感染前水平，感染活泼锥虫的牛在11天内恢复到感染前水平。在感染后第50天接受治疗的感染活泼锥虫的牛恢复较慢。贝尼尔治疗对对照动物的补体水平没有影响。本文讨论了牛锥虫病中这些低补体水平的可能原因及影响。
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