Erkell L J
Exp Cell Biol. 1980;48(5):374-80. doi: 10.1159/000163002.
After exposure to increased oxygen tension for 3 days, cultured mouse neuroblastoma cells were found to undergo morphological differentiation and to significantly increase their ecto-acetylcholinesterase activity. Differentiation could not be blocked by KCN or lipid-soluble antioxidants, indicating that neither an increased respiration, nor an increased oxidation of membrane lipids was responsible for the effect.
在暴露于增高的氧张力3天后，发现培养的小鼠神经母细胞瘤细胞发生形态分化，并显著增加其外源性乙酰胆碱酯酶活性。分化不能被氰化钾或脂溶性抗氧化剂阻断，这表明呼吸增加和膜脂氧化增加均不是造成该效应的原因。
