慢性活动性肝炎患者肝细胞中的乙肝核心抗原
Hepatitis B core antigen in hepatocytes of patients with chronic active hepatitis.
作者信息
Brechot C, Trepo C, Ninova-Bradistilova D, Goudeau A, Degott C, Maupas P, Potet F, Benhamou J P
出版信息
Dig Dis Sci. 1980 Aug;25(8):593-6. doi: 10.1007/BF01318872.
PMID:7398519
Abstract
Hepatitis B core antigen was demonstrated in the hepatocytes of 28 of 40 patients with chronic active hepatitis in whose sera hepatitis B surface antigen was not detectable by radioimmunoassay. This finding suggests that in these patients, despite hepatitis B surface antigen being undetectable in serum, the liver disease is the consequence of chronic infection with hepatitis B virus.
摘要
在40例慢性活动性肝炎患者中，有28例患者血清中的乙型肝炎表面抗原用放射免疫测定法检测不到，但其肝细胞中却检测到了乙型肝炎核心抗原。这一发现表明，在这些患者中，尽管血清中检测不到乙型肝炎表面抗原，但肝脏疾病却是由乙型肝炎病毒慢性感染所致。
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