高脂血症患者的血清胆汁盐浓度会升高吗？
Are serum bile salt concentrations raised in hyperlipidaemia?
作者信息
Beckett G J, Douglas J G, Finlayson N D, Percy-Robb I W
出版信息
Gut. 1980 Mar;21(3):219-22. doi: 10.1136/gut.21.3.219.
Abstract
We have studied serum fasting and postprandial primary bile salt concentrations in a group of 10 consecutive hyperlipidaemic subjects. The efficiency of hepatic bile salt clearance in the same subjects was aslo studied using an injected dose of sodium glycocholate. No increase in serum fasting or postprandial concentrations of the primary bile salts were observed and hepatic bile salt clearance was only marginally abnormal in one subject. The presence of hyperlipidaemia does not invalidate the use of serum conjugated bile salt analysis for the detection of liver diseases.
摘要
我们研究了一组连续的10名高脂血症患者空腹和餐后血清中初级胆汁盐的浓度。同时，使用注射剂量的甘氨胆酸钠对同一组患者肝脏胆汁盐清除效率进行了研究。未观察到空腹或餐后血清中初级胆汁盐浓度的升高，且仅1名患者的肝脏胆汁盐清除率略有异常。高脂血症的存在并不影响血清结合胆汁盐分析在肝病检测中的应用。
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