Dalle M, El Hani A, Delost P
J Endocrinol. 1980 May;85(2):219-27. doi: 10.1677/joe.0.0850219.
The metabolic clearance rate and the binding of cortisol in plasma of male and female guinea-pigs were estimated at five stages between birth and weaning. The metabolic clearance rate for cortisol remained low in both sexes until day 10 post partum but increased to adult values by day 20. The level of free cortisol in plasma and the cortisol binding capacity of the plasma were higher at birth than on day 10 post partum; the values found on day 20 were similar to those of the adult guinea-pig. Surgical stress increased levels of cortisol in plasma on day 20 but not at birth.
在出生至断奶的五个阶段，对雄性和雌性豚鼠血浆中皮质醇的代谢清除率及结合情况进行了评估。在产后第10天之前，两性的皮质醇代谢清除率均较低，但到第20天已升至成年豚鼠的水平。出生时血浆中游离皮质醇水平和血浆皮质醇结合能力高于产后第10天；第20天所测值与成年豚鼠相似。手术应激使第20天血浆中皮质醇水平升高，但出生时则不然。
