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犁鼻器和催乳素在小鼠信息素诱导的延迟着床中的作用。

Involvement of the vomeronasal organ and prolactin in pheromonal induction of delayed implantation in mice.

作者信息

Bellringer J F, Pratt H P, Keverne E B

出版信息

J Reprod Fertil. 1980 May;59(1):223-8. doi: 10.1530/jrf.0.0590223.

DOI:10.1530/jrf.0.0590223
PMID:7401039
Abstract

Pregnancy block caused by exposure of mated female mice to a strange male was significantly reduced by bilateral destruction of the vomeronasal organ. Treatment of newly mated females with alpha-bromocriptine also produced pregnancy block. Pregnancy block also occurred in mated females exposed to strange male odours, but the blastocysts which had failed to implant were still present in the uterus and were viable for up to 15 days after mating. Implantation was induced in such mice by administration of exogenous progesterone and oestradiol.

摘要

将交配过的雌性小鼠暴露于陌生雄性小鼠导致的妊娠阻断,可通过双侧破坏犁鼻器而显著减轻。用α-溴隐亭处理刚交配的雌性小鼠也会产生妊娠阻断。暴露于陌生雄性气味的交配过的雌性小鼠也会出现妊娠阻断,但未能着床的囊胚仍存在于子宫中,并且在交配后长达15天内仍具有活力。通过给予外源性孕酮和雌二醇可诱导此类小鼠着床。

相似文献

1
Involvement of the vomeronasal organ and prolactin in pheromonal induction of delayed implantation in mice.犁鼻器和催乳素在小鼠信息素诱导的延迟着床中的作用。
J Reprod Fertil. 1980 May;59(1):223-8. doi: 10.1530/jrf.0.0590223.
2
Role of the vomeronasal organ and prolactin in the acceleration of puberty in female mice.犁鼻器和催乳素在雌性小鼠青春期加速中的作用。
J Reprod Fertil. 1982 Sep;66(1):101-7. doi: 10.1530/jrf.0.0660101.
3
Bromocriptine-induced implantation during lactation in the rat.溴隐亭诱导大鼠哺乳期着床。
J Reprod Fertil. 1981 May;62(1):181-3. doi: 10.1530/jrf.0.0620181.
4
[Inhibition of nidation in mice by modification of the environment and pheromones. Re-establishment by prolactin and thioproperazine].[通过改变环境和信息素抑制小鼠着床。催乳素和甲硫哒嗪使其恢复]
Ann Endocrinol (Paris). 1982;43(1):41-52.
5
Prolactin suppression during pre and post-implantation periods on rat uterine glucosamine synthase activity.大鼠植入前和植入后时期催乳素抑制对子宫葡萄糖胺合酶活性的影响
Indian J Exp Biol. 1993 Apr;31(4):386-8.
6
3'-deoxyadenosine and implantation of delayed blastocysts in mice.3'-脱氧腺苷与小鼠延迟囊胚的植入
J Endocrinol. 1979 Jun;81(3):351-4. doi: 10.1677/joe.0.0810351.
7
Bromocriptine-induced implantation failure in mice: failure of the stud male to protect pregnancy.溴隐亭诱导的小鼠着床失败:种公鼠未能保护妊娠。
Indian J Exp Biol. 1992 Jul;30(7):648-9.
8
Vomeronasal/accessory olfactory system and pheromonal recognition.犁鼻器/副嗅觉系统与信息素识别。
Chem Senses. 1998 Aug;23(4):491-4. doi: 10.1093/chemse/23.4.491.
9
The effect of bromocriptine during early pregnancy in the rat: inhibition of implantation.溴隐亭对大鼠妊娠早期的影响:抑制着床。
Acta Endocrinol (Copenh). 1980 Jun;94(2):268-72. doi: 10.1530/acta.0.0940268.
10
Restricted exposure of mice to primer pheromones coincident with prolactin surges blocks pregnancy by changing hypothalamic dopamine release.小鼠在催乳素激增时有限地接触引物信息素会通过改变下丘脑多巴胺释放来阻止怀孕。
J Reprod Fertil. 1989 Nov;87(2):553-9. doi: 10.1530/jrf.0.0870553.

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