Lee E C, Truelove S C
World J Surg. 1980;4(2):195-201. doi: 10.1007/BF02393575.
The majority of patients with ulcerative colitis can be managed satisfactorily throughout their lives by medical treatment, but a minority require colectomy. In severe attacks, emergency surgery is often required to save the patient's life. In chronic disease not responding well to medical treatment, elective colectomy will restore the patient to good health. Colectomy is also necessary for certain local complications, such as cancer, severe fistulas, and strictures. Prophylactic colectomy is indicated in patients with long-standing disease in whom there are factors associated with a high risk of developing cancer of the large bowel. For all these indications, it is our opinion that single-stage proctocolectomy is the operation of choice in the great majority of patients. Finally, we consider that the best results are obtained when the physician and the surgeon work together in the closest possible cooperation.
大多数溃疡性结肠炎患者可通过药物治疗在其一生中得到满意的管理,但少数患者需要进行结肠切除术。在严重发作时,常需急诊手术以挽救患者生命。在对药物治疗反应不佳的慢性疾病中,择期结肠切除术可使患者恢复健康。对于某些局部并发症,如癌症、严重瘘管和狭窄,结肠切除术也是必要的。对于存在与患大肠癌高风险相关因素的长期患病患者,应进行预防性结肠切除术。对于所有这些适应证,我们认为在绝大多数患者中,一期直肠结肠切除术是首选的手术方式。最后,我们认为当内科医生和外科医生尽可能密切合作时,可取得最佳效果。